Fibro AMJ™ Day-Time Formula is the most scientifically advanced and complete formula ever developed in the fight against fibromyalgia and arthritis.* This formula contains powerful metabolites and herbal extracts that help in tissue and joint repair¹, energy production², and pain reduction&³.*

Fibromyalgia (FM) is a syndrome characterized by widespread musculoskeletal pain and tenderness at specified sites, fatigue, and unrefreshing sleep. Conditions found to be related to fibromyalgia include:

Fibro AMJ™ Day-Time Formula is a 4Life™ proprietary supplement backed by the latest scientific research. This unique formula contains a powerful blend of ingredients that are essential for proper muscle and joint health.* Here are some of the key ingredients in the Fibro AMJ™ Day-Time Formula, and a brief description of their function.

Magnesium is involved with every major energy production and transport function in the body. Magnesium supplementation has shown beneficial impacts on fatigue and pain4 .

Malic acid is essential in the citric acid cycle (energy production cycle). As it passes through this cycle, it is converted into useable energy (ATP).⁵

Glucosamine and Bovine Cartilage are used in the body to manufacture cartilage components necessary for joint and tissue repair.⁶

Methyl Sulfonyl Methane (MSM) is an important source of dietary sulfur. Sulfur plays an integral part in the proper function of many proteins, hormones, and other substances that are critical in keeping muscles and joints healthy.⁷

Boswellia serrata is a natural anti-inflammatory agent. It has been shown to reduce joint swelling, increase mobility, and decrease morning stiffness.⁸

Vitamin B6 is an important co-factor in the production of several important neurotransmitters such as serotonin, gamma-amino butyric acid (GABA), and dopamine.⁹

N-Acetyl cysteine and cysteine play a critical role in the prevention of skeletal muscle wasting and fatigue conditions.^{10 11}

1. Pain Free. Bucci LR. The Summit Group. Fort Worth, TX. 1995.
2. Lehninger AL, Nelson DL, Cox MM: Principles of Biochemistry, New York, 1993, Worth Publishers.
3. Pain Free. Bucci LR. The Summit Group. Fort Worth, TX. 1995.
4.Muscle intracellular magnesium levels correlate with pain tolerance in  fibromyalgia. Clauw D. Katz KWP, Rajan S. Arthritis & Rheumatism 1994, 37(9)S213.5.
5.Management of fibromyalgia: rationale, for the use of magnesium and malic acid. Abraham, G. E.; Flechas, J. D. Journal of nutritional medicine 1992, 3 (1), 49-59.
6.Therapeutic activity of oral glucosamine sulfate in osteoarthritis: a placebo-controlled double-blind investigation.Drovanti A, Bignamini AA, Rovati, Al.. Clin Ther, 1930; 3(4) 260-272.
7.The MSM Miracle. Enhance your health with organic sulfur. Earl L. Mindell, R.Ph., PhD
8.Lehninger AL, and other: Principles of Biochemistry, ed 2, New York, 1993, Worth.
9.Boswellin,The Anti-inflammatory Phytonutrient. Majeed M, Badmaev V, Gopinathan S, Rajendran R, Norton T. Nutriscience Publishers, Inc., Piscaway, NJ. 1996.
lO. Role of cysteine and glutathione in HIV infection and other diseases associated uqth muscle wasting and immunological dysfunction.Droege W, Holm E. FASEB Journal 1997, 11(13) 1077-1089.
11. N-acetylcysteine inhibits muscle fatigue in humans. Reid MB, Stokic DS, Koch SM, Khawli FA, Leis AA.J Clin Invest 1994, 94(6), 2468-74.

What is Fibro AMJ Night-Time Formula?

Fibro AMJ™ Night-Time Formula is a revolutionary product that works in conjunction with the Fibro AMJ™ Day-Time Formula in the fight against fibromyalgia and arthritis.* This product is specially formulated to help restore normal sleep patterns while supplying your body with important nutrients that aid in tissue health.*

The ability to reach deep sleep is essential to health and wellness. Abnormal sleep patterns, or the inability to reach deep sleep (R.E.M.), is believed to be a major factor associated with fibromyalgia and other musculoskeletal conditions. Some of the common effects found in sleep deprivation studies include muscle pain, fatigue, and hormonal imbalances (i.e. Growth Hormone (GH) release).

Fibro AMJ™ Night-Time Formula contains a powerful blend of ingredients that helps you to relax, prepares you for a good night's sleep, and aids in muscle tissue repair.* Below are some of the key ingredients in the Fibro AMJ TM Night-Time Formula, and a brief description of their function.

Key Ingredients:
Melatonin is a hormone that assists us in attaining deep levels of sleep. Melatonin regulates the sleep-wake cycle, helps increase sleep onset, helps our bodies to sleep all night long, and helps us reach deep sleep (REM sleep).¹

Griffonia simplicifolia (natural source of 5-hydroxytryptophan or 5-HTP) is a plant rich in 5-HTP. 5-HTP has been effective against many conditions of fibromyalgia, including reducing muscle pain, anxiety, and pain intensity. It also has shown to help induce sleep, improve sleep quality, and reduce fatigue.²

Pregnenolone is one of the critical neurosteroids that has the ability to modify EEG sleep in humans. This also suggests one of pregnenolone's potential benefits as a memory enhancer.³

St. John's Wort has proven effective in helping to calm the body and promoting positive mood and sleep patterns.⁴

Vitamin B6 is an important co-factor in the production of several important neurotransmitters such as serotonin, gamma-amino butyric acid (GABA), and dopamine. ⁵

Creatine is a nutrient naturally found in our bodies. It is made from three amino acids (arginine, glycine, and methionine). Creatine is used in our muscles to create energy: Our ability to create energy (adenosine triphosphate or ATP) depends upon our creatine supply. Creatine helps restore energy in fatigued muscles.⁶

Kava kava is used for its natural calming effects. Kava helps you relax and allows for a good night's rest.⁷

*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

 

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REFERENCES

1. Efficacy of melatonin is a sleep-promoting agent. Zhdanova IV, Wurtman RJ. J Biol Rhythms 1997, 12(6),644-50.
2. Double-blind study of 5-hydroxyptophan versus placebo in the treatment of primary fibromyalgia syndrome. Caruso I, Sarzi Puttini P, Cazzola M, Azzolini V. J Int Med Res 1990, 18(3), 201-9.
3.Neurosteroid pregnenolone induces sleep-EEG changes in man compatible with inverse agonist GABAA-receptor modulation. Steiger A, Trachsel L, Guldner J, Hemmeter U, Rothe, B, Rupprecht R, Vedder H, Holsboer F. Brain Res l993, 615, .267-274.
4.Biologically active and other chemical constituents of the herb of Hypericum perforatum L. Nahrstedt A, Butterweck V. Pharmacopsychiatry 1997, 30(Suppl20),129-34.
5.Lehninger AL, and other: Principles of Biochemistry, ed 2, New York, 1993, Worth. 6.Effects of oral creatine supplementation on power output and fatigue during bicycle ergometry. Cook W, Grandjean P, Barnes W. JAppl Physiol 78(2):670-73, 1995.
7.Effect of a special kava extract in patients with anxiety, tension, and excitation states of non-psychotic genesis. Double blind study with placebos over 4 weeks. l Kinzler E, Kromer J, Lehmann E. Arzneimittelforschung 1991, 41(6), 584--8.